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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK17
All Species:
27.27
Human Site:
Y269
Identified Species:
54.55
UniProt:
Q00537
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00537
NP_002586.2
523
59582
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Chimpanzee
Pan troglodytes
XP_001146785
513
58578
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
L254
I
N
M
H
N
V
K
L
F
L
F
Q
L
L
R
Dog
Lupus familis
XP_539731
541
61618
Y287
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0D0
523
59488
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Rat
Rattus norvegicus
O35831
523
59414
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510894
523
59528
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Chicken
Gallus gallus
XP_416161
516
58803
Y269
S
L
T
L
V
F
E
Y
L
D
K
D
L
K
Q
Frog
Xenopus laevis
Q6DJM7
435
49211
L203
P
E
N
V
K
L
F
L
F
Q
L
L
R
G
L
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
F185
H
S
Y
N
I
R
L
F
M
F
Q
L
L
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
I63
K
E
M
N
H
G
N
I
V
R
L
H
D
V
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
I63
K
E
M
Q
H
S
N
I
V
K
L
Q
D
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
67.3
94.6
N.A.
98.6
96.3
N.A.
98.4
95.7
43.4
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.8
80.1
95.1
N.A.
99.8
97.7
N.A.
99.4
97.1
56.9
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
6.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
31.5
N.A.
31.5
N.A.
N.A.
Protein Similarity:
N.A.
44.5
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
59
0
59
17
0
0
% D
% Glu:
0
25
0
0
0
0
59
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
59
9
9
17
9
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% G
% His:
9
0
0
9
17
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
17
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
9
0
9
0
0
9
59
0
0
59
0
% K
% Leu:
0
59
0
59
0
9
9
17
59
9
25
17
75
9
9
% L
% Met:
0
0
25
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
9
9
17
9
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
9
17
0
0
59
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
0
0
9
9
9
% R
% Ser:
59
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
59
9
0
0
17
0
0
0
0
17
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _